/* ========================================
   Neonatal Hyperbilirubinemia Calculator
   Medical-Grade Premium Styling
   ======================================== */

:root {
    /* Primary Colors - Medical Blue Palette */
    --primary-blue: #2563eb;
    --primary-blue-dark: #1e40af;
    --primary-blue-light: #3b82f6;
    --primary-blue-lighter: #dbeafe;
    
    /* Accent Colors */
    --accent-teal: #0891b2;
    --accent-green: #059669;
    --accent-amber: #d97706;
    --accent-red: #dc2626;
    
    /* Neutral Colors */
    --gray-50: #f9fafb;
    --gray-100: #f3f4f6;
    --gray-200: #e5e7eb;
    --gray-300: #d1d5db;
    --gray-400: #9ca3af;
    --gray-500: #6b7280;
    --gray-600: #4b5563;
    --gray-700: #374151;
    --gray-800: #1f2937;
    --gray-900: #111827;
    
    /* Clinical Status Colors */
    --status-safe: #10b981;
    --status-caution: #f59e0b;
    --status-warning: #ef4444;
    --status-critical: #991b1b;
    
    /* Backgrounds */
    --bg-primary: #ffffff;
    --bg-secondary: var(--gray-50);
    --bg-card: #ffffff;
    
    /* Shadows */
    --shadow-sm: 0 1px 2px 0 rgba(0, 0, 0, 0.05);
    --shadow-md: 0 4px 6px -1px rgba(0, 0, 0, 0.1), 0 2px 4px -1px rgba(0, 0, 0, 0.06);
    --shadow-lg: 0 10px 15px -3px rgba(0, 0, 0, 0.1), 0 4px 6px -2px rgba(0, 0, 0, 0.05);
    --shadow-xl: 0 20px 25px -5px rgba(0, 0, 0, 0.1), 0 10px 10px -5px rgba(0, 0, 0, 0.04);
    
    /* Transitions */
    --transition-fast: 150ms ease-in-out;
    --transition-normal: 250ms ease-in-out;
    --transition-slow: 350ms ease-in-out;
    
    /* Spacing */
    --spacing-xs: 0.5rem;
    --spacing-sm: 0.75rem;
    --spacing-md: 1rem;
    --spacing-lg: 1.5rem;
    --spacing-xl: 2rem;
    --spacing-2xl: 3rem;
    
    /* Border Radius */
    --radius-sm: 0.375rem;
    --radius-md: 0.5rem;
    --radius-lg: 0.75rem;
    --radius-xl: 1rem;
}

/* ========================================
   Global Styles
   ======================================== */

* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

body {
    font-family: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'Helvetica Neue', Arial, sans-serif;
    background: linear-gradient(135deg, #1e3a8a 0%, #0891b2 50%, #06b6d4 100%);
    background-attachment: fixed;
    color: var(--gray-900);
    line-height: 1.6;
    min-height: 100vh;
    padding: var(--spacing-lg);
}

.container {
    max-width: 1400px;
    margin: 0 auto;
    background: var(--bg-card);
    border-radius: var(--radius-xl);
    box-shadow: 0 20px 40px rgba(0, 0, 0, 0.15);
    overflow: hidden;
}

/* ========================================
   Header
   ======================================== */

header {
    background: linear-gradient(135deg, var(--primary-blue) 0%, var(--accent-teal) 100%);
    color: white;
    padding: var(--spacing-2xl) var(--spacing-xl);
    text-align: center;
    box-shadow: 0 8px 32px rgba(0, 0, 0, 0.15);
}

header h1 {
    font-size: 2.75rem;
    font-weight: 800;
    margin-bottom: var(--spacing-sm);
    text-shadow: 0 2px 8px rgba(0, 0, 0, 0.15);
    letter-spacing: -0.5px;
}

.subtitle {
    font-size: 1.125rem;
    font-weight: 600;
    opacity: 0.98;
    margin-bottom: var(--spacing-lg);
    letter-spacing: 0.3px;
}

.telegram-link {
    color: white;
    text-decoration: none;
    transition: all var(--transition-fast);
    padding: 0.5rem 1rem;
    border: 2px solid rgba(255, 255, 255, 0.6);
    border-radius: var(--radius-md);
    display: inline-block;
    font-weight: 600;
    background: rgba(255, 255, 255, 0.1);
}

.telegram-link:hover {
    opacity: 1;
    text-decoration: none;
    background: rgba(255, 255, 255, 0.2);
    border-color: white;
    transform: translateY(-2px);
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.2);
}

.disclaimer {
    background: rgba(255, 255, 255, 0.15);
    backdrop-filter: blur(10px);
    border: 1px solid rgba(255, 255, 255, 0.2);
    border-radius: var(--radius-lg);
    padding: var(--spacing-md) var(--spacing-lg);
    margin-top: var(--spacing-lg);
    font-size: 0.875rem;
    line-height: 1.5;
}

.disclaimer strong {
    display: block;
    margin-bottom: var(--spacing-xs);
    font-size: 1rem;
}

/* ========================================
   Main Content
   ======================================== */

main {
    padding: var(--spacing-2xl) var(--spacing-xl);
}

/* ========================================
   Cards
   ======================================== */

.card {
    background: var(--bg-card);
    border-radius: var(--radius-lg);
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.06);
    padding: var(--spacing-xl);
    margin-bottom: var(--spacing-xl);
    border: 1px solid var(--gray-200);
    transition: all var(--transition-normal);
}

.card:hover {
    transform: translateY(-3px);
    box-shadow: 0 8px 24px rgba(0, 0, 0, 0.1);
}

.card h2 {
    font-size: 1.75rem;
    font-weight: 800;
    color: var(--gray-900);
    margin-bottom: var(--spacing-lg);
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
    letter-spacing: -0.5px;
}

/* ========================================
   Form Elements
   ======================================== */

.form-group {
    margin-bottom: var(--spacing-lg);
}

.form-group label {
    display: block;
    font-weight: 700;
    color: var(--gray-800);
    margin-bottom: var(--spacing-sm);
    font-size: 0.875rem;
    text-transform: uppercase;
    letter-spacing: 0.5px;
}

.input-row {
    display: flex;
    gap: var(--spacing-md);
    align-items: center;
}

.input-wrapper {
    position: relative;
    flex: 1;
}

.input-wrapper.full-width {
    flex: 2;
}

.input-wrapper input {
    width: 100%;
    padding: 1rem 1.25rem;
    border: 2px solid var(--gray-300);
    border-radius: 10px;
    font-size: 1rem;
    transition: all var(--transition-fast);
    background: var(--bg-primary);
    font-weight: 500;
}

.input-wrapper input:hover {
    border-color: var(--primary-blue);
    box-shadow: 0 2px 8px rgba(37, 99, 235, 0.1);
}

.input-wrapper input:focus {
    outline: none;
    border-color: var(--primary-blue);
    box-shadow: 0 0 0 4px var(--primary-blue-lighter);
    background: var(--bg-primary);
}

.input-suffix {
    position: absolute;
    right: 1rem;
    top: 50%;
    transform: translateY(-50%);
    color: var(--gray-500);
    font-size: 0.875rem;
    pointer-events: none;
}

input[type="number"],
input[type="datetime-local"] {
    padding: 1rem 1.25rem;
    border: 2px solid var(--gray-300);
    border-radius: 10px;
    font-size: 1rem;
    transition: all var(--transition-fast);
    background: var(--bg-primary);
    width: 100%;
    font-weight: 500;
}

input[type="number"]:hover,
input[type="datetime-local"]:hover {
    border-color: var(--primary-blue);
    box-shadow: 0 2px 8px rgba(37, 99, 235, 0.1);
}

input[type="number"]:focus,
input[type="datetime-local"]:focus {
    outline: none;
    border-color: var(--primary-blue);
    box-shadow: 0 0 0 4px var(--primary-blue-lighter);
}

select {
    padding: 1rem 1.25rem;
    border: 2px solid var(--gray-300);
    border-radius: 10px;
    font-size: 1rem;
    background: var(--bg-primary);
    cursor: pointer;
    transition: all var(--transition-fast);
    min-width: 140px;
    font-weight: 600;
    color: var(--gray-900);
    appearance: none;
    background-image: url("data:image/svg+xml;charset=UTF-8,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 24 24' fill='none' stroke='currentColor' stroke-width='2' stroke-linecap='round' stroke-linejoin='round'%3e%3cpolyline points='6 9 12 15 18 9'%3e%3c/polyline%3e%3c/svg%3e");
    background-repeat: no-repeat;
    background-position: right 1rem center;
    background-size: 1.2em;
    padding-right: 2.5rem;
}

select:hover {
    border-color: var(--primary-blue);
    box-shadow: 0 4px 12px rgba(37, 99, 235, 0.15);
}

select:focus {
    outline: none;
    border-color: var(--primary-blue);
    box-shadow: 0 0 0 4px var(--primary-blue-lighter);
}

select option {
    padding: 0.75rem;
    background: white;
    color: var(--gray-900);
    font-weight: 500;
}

.calculated-value {
    background: var(--primary-blue-lighter);
    border: 2px solid var(--primary-blue);
    border-radius: var(--radius-md);
    padding: 0.75rem 1rem;
    font-size: 1.125rem;
    font-weight: 600;
    color: var(--primary-blue-dark);
}

/* ========================================
   Risk Factors
   ======================================== */

.risk-description {
    color: var(--gray-600);
    margin-bottom: var(--spacing-lg);
    font-size: 0.9375rem;
}

.risk-factors {
    display: grid;
    gap: var(--spacing-md);
    margin-bottom: var(--spacing-lg);
}

.checkbox-label {
    display: flex;
    align-items: flex-start;
    gap: var(--spacing-md);
    padding: var(--spacing-md) var(--spacing-lg);
    background: var(--gray-50);
    border: 2px solid var(--gray-200);
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: all var(--transition-fast);
    position: relative;
}

.checkbox-label:hover {
    background: var(--gray-100);
    border-color: var(--primary-blue);
}

.checkbox-label input[type="checkbox"] {
    position: absolute;
    opacity: 0;
}

.checkmark {
    width: 20px;
    height: 20px;
    border: 2px solid var(--gray-400);
    border-radius: var(--radius-sm);
    flex-shrink: 0;
    transition: all var(--transition-fast);
    position: relative;
}

.checkbox-label input[type="checkbox"]:checked ~ .checkmark {
    background: var(--primary-blue);
    border-color: var(--primary-blue);
}

.checkbox-label input[type="checkbox"]:checked ~ .checkmark::after {
    content: '✓';
    position: absolute;
    color: white;
    font-weight: bold;
    font-size: 14px;
    top: 50%;
    left: 50%;
    transform: translate(-50%, -50%);
}

.label-text {
    color: var(--gray-700);
    font-size: 0.9375rem;
    line-height: 1.5;
}

.risk-status {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
    padding: var(--spacing-md) var(--spacing-lg);
    background: var(--gray-50);
    border-radius: var(--radius-md);
    border-left: 4px solid var(--status-safe);
}

.risk-status.has-risk {
    background: #fef3c7;
    border-left-color: var(--status-warning);
}

.status-indicator {
    width: 12px;
    height: 12px;
    border-radius: 50%;
    background: var(--status-safe);
    flex-shrink: 0;
    transition: all var(--transition-fast);
}

.status-indicator.no-risk {
    background: var(--status-safe);
}

.status-indicator.has-risk {
    background: var(--status-warning);
    animation: pulse 2s ease-in-out infinite;
}

@keyframes pulse {
    0%, 100% { opacity: 1; }
    50% { opacity: 0.5; }
}

#riskStatusText {
    font-weight: 500;
    color: var(--gray-700);
}

/* ========================================
   Calculate Button
   ======================================== */

.calculate-btn {
    width: 100%;
    padding: 1.5rem 2.5rem;
    background: linear-gradient(135deg, #2563eb 0%, #0891b2 100%);
    color: white;
    border: none;
    border-radius: 12px;
    font-size: 1.25rem;
    font-weight: 800;
    cursor: pointer;
    transition: all 300ms cubic-bezier(0.4, 0, 0.2, 1);
    box-shadow: 0 8px 30px rgba(37, 99, 235, 0.35);
    margin-bottom: var(--spacing-xl);
    letter-spacing: 0.7px;
    position: relative;
    overflow: hidden;
}

.calculate-btn::before {
    content: '';
    position: absolute;
    top: -50%;
    left: -50%;
    width: 200%;
    height: 200%;
    background: linear-gradient(45deg, transparent, rgba(255, 255, 255, 0.3), transparent);
    transform: rotate(45deg);
    animation: shimmer 3s infinite;
}

@keyframes shimmer {
    0% { transform: translateX(-100%) translateY(-100%) rotate(45deg); }
    100% { transform: translateX(100%) translateY(100%) rotate(45deg); }
}

.calculate-btn:hover {
    transform: translateY(-6px);
    box-shadow: 0 14px 40px rgba(37, 99, 235, 0.45);
    background: linear-gradient(135deg, #1e40af 0%, #0891b2 100%);
}

.calculate-btn:active {
    transform: translateY(-2px);
    box-shadow: 0 6px 20px rgba(37, 99, 235, 0.3);
}

.calculate-btn span {
    display: flex;
    align-items: center;
    justify-content: center;
    gap: var(--spacing-sm);
    position: relative;
    z-index: 1;
}

/* ========================================
   Tabs
   ======================================== */

.tabs {
    display: flex;
    gap: var(--spacing-xs);
    margin-bottom: var(--spacing-xl);
    border-bottom: 2px solid var(--gray-200);
    background: var(--gray-50);
    padding: var(--spacing-xs);
    border-radius: 10px;
}

.tab-btn {
    padding: 0.85rem 1.5rem;
    background: transparent;
    border: none;
    border-radius: 8px;
    font-weight: 700;
    color: var(--gray-600);
    cursor: pointer;
    transition: all var(--transition-fast);
    font-size: 1rem;
    letter-spacing: 0.3px;
}

.tab-btn:hover {
    color: var(--primary-blue);
    background: rgba(37, 99, 235, 0.08);
}

.tab-btn.active {
    color: white;
    background: linear-gradient(135deg, #2563eb 0%, #0891b2 100%);
    box-shadow: 0 4px 12px rgba(37, 99, 235, 0.4);
    transform: translateY(-2px);
}

.tab-content {
    display: none;
}

.tab-content.active {
    display: block;
    animation: fadeIn var(--transition-normal);
}

.tab-content.ga-outside-range {
    opacity: 0.7;
}

@keyframes fadeIn {
    from { opacity: 0; transform: translateY(10px); }
    to { opacity: 1; transform: translateY(0); }
}

/* ========================================
   Results
   ======================================== */

.result-header {
    margin-bottom: var(--spacing-xl);
    text-align: center;
}

.result-header h3 {
    font-size: 1.5rem;
    color: var(--gray-900);
    margin-bottom: var(--spacing-xs);
}

.result-header p {
    color: var(--gray-600);
    font-size: 0.9375rem;
}

.threshold-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: var(--spacing-lg);
    margin-bottom: var(--spacing-xl);
}

.threshold-box {
    padding: var(--spacing-xl);
    border-radius: var(--radius-lg);
    text-align: center;
    border: 2px solid;
    background: linear-gradient(135deg, rgba(255, 255, 255, 0.95), rgba(255, 255, 255, 0.7));
    backdrop-filter: blur(10px);
    transition: all var(--transition-normal);
    box-shadow: 0 2px 8px rgba(0, 0, 0, 0.04);
}

.threshold-box:hover {
    transform: translateY(-6px);
    box-shadow: 0 8px 24px rgba(0, 0, 0, 0.12);
}

.threshold-box.phototherapy {
    border-color: var(--accent-amber);
    box-shadow: 0 4px 20px rgba(217, 119, 6, 0.15);
}

.threshold-box.phototherapy:hover {
    box-shadow: 0 8px 28px rgba(217, 119, 6, 0.2);
}

.threshold-box.exchange {
    border-color: var(--accent-red);
    box-shadow: 0 4px 20px rgba(220, 38, 38, 0.15);
}

.threshold-box.exchange:hover {
    box-shadow: 0 8px 28px rgba(220, 38, 38, 0.2);
}

.threshold-label {
    font-size: 0.75rem;
    font-weight: 700;
    text-transform: uppercase;
    letter-spacing: 0.75px;
    margin-bottom: var(--spacing-sm);
    color: var(--gray-700);
}

.threshold-value {
    font-size: 2.75rem;
    font-weight: 800;
    margin-bottom: var(--spacing-xs);
    letter-spacing: -1px;
}

.threshold-box.phototherapy .threshold-value {
    color: var(--accent-amber);
    text-shadow: 0 2px 4px rgba(217, 119, 6, 0.1);
}

.threshold-box.exchange .threshold-value {
    color: var(--accent-red);
    text-shadow: 0 2px 4px rgba(220, 38, 38, 0.1);
}

.threshold-unit {
    font-size: 1rem;
    color: var(--gray-600);
    font-weight: 600;
}

/* ========================================
   Patient Level Box
   ======================================== */

.patient-level-box {
    background: linear-gradient(135deg, var(--primary-blue-lighter), #e0f2fe);
    border: 2px solid var(--primary-blue);
    border-radius: var(--radius-lg);
    padding: var(--spacing-xl);
    text-align: center;
    margin-bottom: var(--spacing-xl);
    box-shadow: 0 4px 16px rgba(37, 99, 235, 0.1);
    transition: all var(--transition-normal);
}

.patient-level-box:hover {
    box-shadow: 0 6px 20px rgba(37, 99, 235, 0.15);
}

.level-header {
    font-size: 0.8rem;
    font-weight: 700;
    text-transform: uppercase;
    letter-spacing: 0.75px;
    color: var(--primary-blue-dark);
    margin-bottom: var(--spacing-sm);
}

.level-value {
    font-size: 2.25rem;
    font-weight: 800;
    color: var(--primary-blue-dark);
    margin-bottom: var(--spacing-sm);
    letter-spacing: -0.5px;
}

.level-status {
    font-weight: 700;
    font-size: 1.125rem;
    margin-top: var(--spacing-md);
    display: block;
    min-height: 1.5rem;
    letter-spacing: 0.5px;
}

.level-status.safe {
    color: var(--status-safe);
}

.level-status.caution {
    color: var(--accent-amber);
}

.level-status.warning {
    color: var(--accent-red);
}

.level-status.critical {
    color: var(--status-critical);
}

/* ========================================
   Recommendation Box
   ======================================== */

.recommendation-box {
    background: var(--gray-50);
    border-left: 5px solid var(--primary-blue);
    border-radius: var(--radius-lg);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-xl);
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.06);
    transition: all var(--transition-normal);
}

.recommendation-box:hover {
    box-shadow: 0 6px 16px rgba(0, 0, 0, 0.1);
}

.recommendation-box h4 {
    font-size: 1.25rem;
    color: var(--gray-900);
    margin-bottom: var(--spacing-md);
    font-weight: 700;
}

.recommendation-box p {
    color: var(--gray-700);
    line-height: 1.8;
    font-size: 1rem;
}

.recommendation-box.safe {
    background: #f0fdf4;
    border-left-color: var(--status-safe);
}

.recommendation-box.caution {
    background: #fffbeb;
    border-left-color: var(--accent-amber);
}

.recommendation-box.warning {
    background: #fef3c7;
    border-left-color: var(--accent-amber);
}

.recommendation-box.critical {
    background: #fee2e2;
    border-left-color: var(--status-critical);
    box-shadow: 0 4px 12px rgba(220, 38, 38, 0.1);
}

/* ========================================
   Charts
   ======================================== */

.chart-container {
    background: var(--bg-primary);
    padding: var(--spacing-xl);
    border-radius: var(--radius-lg);
    border: 1px solid var(--gray-200);
    margin-top: var(--spacing-xl);
    box-shadow: 0 2px 8px rgba(0, 0, 0, 0.04);
    transition: all var(--transition-normal);
    position: relative;
    width: 100%;
    max-width: 100%;
}

.chart-container:hover {
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.08);
}

.chart-container canvas {
    max-width: 100%;
    height: auto !important;
    display: block;
}

#aapChart,
#niceChart,
#comparisonChart {
    max-width: 100%;
    height: auto;
    width: 100% !important;
}

/* ========================================
   Comparison Table
   ======================================== */

.comparison-table {
    width: 100%;
    border-collapse: collapse;
    margin-bottom: var(--spacing-xl);
    background: var(--bg-primary);
    border-radius: var(--radius-lg);
    overflow: hidden;
    box-shadow: var(--shadow-sm);
}

.comparison-table thead {
    background: linear-gradient(135deg, var(--primary-blue), var(--accent-teal));
    color: white;
}

.comparison-table th {
    padding: var(--spacing-md) var(--spacing-lg);
    text-align: left;
    font-weight: 600;
    font-size: 0.9375rem;
}

.comparison-table tbody tr {
    border-bottom: 1px solid var(--gray-200);
    transition: background var(--transition-fast);
}

.comparison-table tbody tr:hover {
    background: var(--gray-50);
}

.comparison-table tbody tr:last-child {
    border-bottom: none;
}

.comparison-table td {
    padding: var(--spacing-md) var(--spacing-lg);
    color: var(--gray-700);
    font-size: 0.9375rem;
}

.comparison-table td:first-child {
    font-weight: 600;
    color: var(--gray-900);
}

/* ========================================
   Clinical Actions
   ======================================== */

.action-card ul {
    list-style: none;
    padding: 0;
}

.action-card li {
    padding: var(--spacing-md) var(--spacing-lg);
    background: var(--gray-50);
    border-left: 4px solid var(--primary-blue);
    border-radius: var(--radius-md);
    margin-bottom: var(--spacing-md);
    transition: all var(--transition-fast);
}

.action-card li:hover {
    background: var(--gray-100);
    transform: translateX(4px);
}

.action-card li.critical {
    background: #fee2e2;
    border-left-color: var(--accent-red);
}

.action-card li.warning {
    background: #fef3c7;
    border-left-color: var(--accent-amber);
}

.action-card li.safe {
    background: #d1fae5;
    border-left-color: var(--status-safe);
}

/* ========================================
   Info Sections
   ======================================== */

.info-section {
    margin-bottom: var(--spacing-xl);
}

.info-section:last-child {
    margin-bottom: 0;
}

.info-section h4 {
    font-size: 1.125rem;
    color: var(--gray-900);
    margin-bottom: var(--spacing-md);
    padding-bottom: var(--spacing-sm);
    border-bottom: 2px solid var(--gray-200);
}

.info-section ul {
    list-style: none;
    padding: 0;
}

.info-section li {
    padding: var(--spacing-sm) 0;
    padding-left: var(--spacing-lg);
    position: relative;
    color: var(--gray-700);
    line-height: 1.6;
}

.info-section li::before {
    content: '→';
    position: absolute;
    left: 0;
    color: var(--primary-blue);
    font-weight: bold;
}

/* ========================================
   Footer
   ======================================== */

footer {
    background: var(--gray-900);
    color: var(--gray-300);
    padding: var(--spacing-2xl) var(--spacing-xl);
}

.references h3 {
    color: white;
    font-size: 1.25rem;
    margin-bottom: var(--spacing-lg);
}

.references ol {
    padding-left: var(--spacing-xl);
    margin-bottom: var(--spacing-xl);
}

.references li {
    margin-bottom: var(--spacing-md);
    line-height: 1.7;
}

.references em {
    color: var(--gray-400);
}

.copyright {
    text-align: center;
    padding-top: var(--spacing-lg);
    border-top: 1px solid var(--gray-700);
    font-size: 0.875rem;
    color: var(--gray-400);
}

.copyright a {
    color: var(--primary-blue);
    text-decoration: none;
    transition: color var(--transition-fast);
}

.copyright a:hover {
    color: var(--primary-blue-light);
    text-decoration: underline;
}

/* ========================================
   Responsive Design
   ======================================== */

@media (max-width: 768px) {
    body {
        padding: var(--spacing-sm);
    }

    .container {
        border-radius: var(--radius-lg);
    }

    header {
        padding: var(--spacing-xl) var(--spacing-md);
    }

    header h1 {
        font-size: 1.75rem;
        margin-bottom: var(--spacing-xs);
    }

    .subtitle {
        font-size: 0.95rem;
        margin-bottom: var(--spacing-md);
    }

    .disclaimer {
        padding: var(--spacing-md) var(--spacing-sm);
        font-size: 0.8rem;
    }

    main {
        padding: var(--spacing-lg) var(--spacing-md);
    }

    .card {
        padding: var(--spacing-lg);
        margin-bottom: var(--spacing-lg);
    }

    .card h2 {
        font-size: 1.25rem;
        margin-bottom: var(--spacing-md);
    }

    .form-group {
        margin-bottom: var(--spacing-md);
    }

    .form-group label {
        font-size: 0.75rem;
        margin-bottom: var(--spacing-xs);
    }

    .input-row {
        gap: var(--spacing-sm);
        flex-direction: column;
    }

    .input-wrapper {
        width: 100%;
    }

    .input-wrapper input,
    input[type="number"],
    input[type="datetime-local"] {
        padding: 0.75rem 1rem;
        font-size: 1rem;
        border-radius: 8px;
    }

    select {
        padding: 0.75rem 1rem;
        border-radius: 8px;
        font-size: 0.95rem;
        min-width: 100px;
    }

    .input-suffix {
        font-size: 0.75rem;
    }

    .calculated-value {
        padding: 0.6rem 0.8rem;
        font-size: 1rem;
    }

    .checkbox-label {
        font-size: 0.9rem;
        padding: var(--spacing-sm) 0;
    }

    .calculate-btn {
        padding: 1.25rem 2rem;
        font-size: 1.1rem;
        margin-bottom: var(--spacing-lg);
    }

    .tabs {
        gap: var(--spacing-xs);
        margin-bottom: var(--spacing-lg);
        flex-direction: row;
        flex-wrap: wrap;
    }

    .tab-btn {
        padding: var(--spacing-sm) var(--spacing-md);
        font-size: 0.9rem;
        flex: 1;
        min-width: 80px;
    }

    .threshold-grid {
        grid-template-columns: 1fr;
        gap: var(--spacing-md);
    }

    .threshold-box {
        padding: var(--spacing-lg);
    }

    .threshold-label {
        font-size: 0.7rem;
        margin-bottom: var(--spacing-xs);
    }

    .threshold-value {
        font-size: 2rem;
        margin-bottom: var(--spacing-xs);
    }

    .threshold-unit {
        font-size: 0.9rem;
    }

    .patient-level-box {
        padding: var(--spacing-lg);
        margin-bottom: var(--spacing-lg);
    }

    .level-header {
        font-size: 0.75rem;
        margin-bottom: var(--spacing-xs);
    }

    .level-value {
        font-size: 1.75rem;
        margin-bottom: var(--spacing-xs);
    }

    .level-status {
        font-size: 1rem;
        margin-top: var(--spacing-sm);
    }

    .recommendation-box {
        padding: var(--spacing-md);
        margin-bottom: var(--spacing-lg);
        border-left: 4px solid;
    }

    .recommendation-box h4 {
        font-size: 1rem;
        margin-bottom: var(--spacing-sm);
    }

    .recommendation-box p {
        font-size: 0.9rem;
        line-height: 1.6;
    }

    .chart-container {
        padding: var(--spacing-md);
        margin-top: var(--spacing-lg);
        width: 100%;
        max-width: 100%;
    }

    #aapChart,
    #niceChart,
    #comparisonChart {
        width: 100%;
        height: auto;
    }

    .result-header h3 {
        font-size: 1.25rem;
    }

    .result-header p {
        font-size: 0.85rem;
    }

    .comparison-table {
        font-size: 0.85rem;
    }

    .comparison-table th,
    .comparison-table td {
        padding: var(--spacing-sm);
    }

    .info-card h2 {
        font-size: 1.25rem;
    }

    .info-section h4 {
        font-size: 1rem;
        margin-top: var(--spacing-md);
    }

    .info-section ul {
        font-size: 0.9rem;
        padding-left: 1.5rem;
    }

    .info-section li {
        margin-bottom: var(--spacing-xs);
    }

    footer {
        padding: var(--spacing-lg) var(--spacing-md);
    }

    footer h3 {
        font-size: 1.1rem;
    }

    footer ol,
    footer p {
        font-size: 0.85rem;
    }

    footer a {
        font-size: 0.85rem;
    }
}

@media (max-width: 480px) {
    body {
        padding: var(--spacing-xs);
    }

    .container {
        border-radius: var(--radius-md);
    }

    header {
        padding: var(--spacing-lg) var(--spacing-sm);
    }

    header h1 {
        font-size: 1.4rem;
        margin-bottom: var(--spacing-xs);
    }

    .subtitle {
        font-size: 0.85rem;
        margin-bottom: var(--spacing-sm);
    }

    .disclaimer {
        padding: var(--spacing-sm);
        font-size: 0.75rem;
        margin-top: var(--spacing-sm);
    }

    main {
        padding: var(--spacing-md) var(--spacing-sm);
    }

    .card {
        padding: var(--spacing-md);
        margin-bottom: var(--spacing-md);
    }

    .card h2 {
        font-size: 1.1rem;
        margin-bottom: var(--spacing-sm);
        gap: var(--spacing-xs);
    }

    .form-group {
        margin-bottom: var(--spacing-sm);
    }

    .form-group label {
        font-size: 0.7rem;
        margin-bottom: var(--spacing-xs);
    }

    .input-row {
        gap: var(--spacing-xs);
        flex-direction: column;
    }

    .input-wrapper {
        width: 100%;
    }

    .input-wrapper input,
    input[type="number"],
    input[type="datetime-local"] {
        padding: 0.7rem 0.9rem;
        font-size: 16px;
        border-radius: 6px;
    }

    select {
        padding: 0.7rem 0.9rem;
        border-radius: 6px;
        font-size: 0.9rem;
        width: 100%;
        min-width: auto;
    }

    .input-suffix {
        font-size: 0.7rem;
        right: 0.75rem;
    }

    .calculated-value {
        padding: 0.5rem 0.75rem;
        font-size: 0.95rem;
    }

    .checkbox-label {
        font-size: 0.85rem;
        padding: var(--spacing-xs) 0;
    }

    .risk-factors {
        gap: var(--spacing-xs);
    }

    .risk-status {
        margin-top: var(--spacing-sm);
    }

    .calculate-btn {
        padding: 1.1rem 1.8rem;
        font-size: 1rem;
        margin-bottom: var(--spacing-md);
        border-radius: 10px;
    }

    .tabs {
        gap: var(--spacing-xs);
        margin-bottom: var(--spacing-md);
        border-bottom: 1px solid var(--gray-200);
    }

    .tab-btn {
        padding: var(--spacing-xs) var(--spacing-sm);
        font-size: 0.8rem;
        flex: 1;
        min-width: auto;
    }

    .threshold-grid {
        grid-template-columns: 1fr;
        gap: var(--spacing-sm);
    }

    .threshold-box {
        padding: var(--spacing-md);
    }

    .threshold-label {
        font-size: 0.65rem;
        margin-bottom: var(--spacing-xs);
        letter-spacing: 0.3px;
    }

    .threshold-value {
        font-size: 1.75rem;
        margin-bottom: var(--spacing-xs);
    }

    .threshold-unit {
        font-size: 0.85rem;
    }

    .patient-level-box {
        padding: var(--spacing-md);
        margin-bottom: var(--spacing-md);
    }

    .level-header {
        font-size: 0.7rem;
        margin-bottom: var(--spacing-xs);
    }

    .level-value {
        font-size: 1.5rem;
        margin-bottom: var(--spacing-xs);
    }

    .level-status {
        font-size: 0.95rem;
        margin-top: var(--spacing-xs);
    }

    .recommendation-box {
        padding: var(--spacing-sm);
        margin-bottom: var(--spacing-md);
        border-left: 3px solid;
    }

    .recommendation-box h4 {
        font-size: 0.95rem;
        margin-bottom: var(--spacing-xs);
    }

    .recommendation-box p {
        font-size: 0.85rem;
        line-height: 1.5;
    }

    .chart-container {
        padding: var(--spacing-sm);
        margin-top: var(--spacing-md);
        width: 100%;
        max-width: 100%;
    }

    #aapChart,
    #niceChart,
    #comparisonChart {
        width: 100%;
        height: auto;
        max-width: 100%;
    }

    .result-header h3 {
        font-size: 1.1rem;
        margin-bottom: var(--spacing-xs);
    }

    .result-header p {
        font-size: 0.8rem;
        margin: 0;
    }

    .comparison-table {
        font-size: 0.8rem;
        width: 100%;
    }

    .comparison-table th,
    .comparison-table td {
        padding: var(--spacing-xs) var(--spacing-xs);
    }

    .info-card h2 {
        font-size: 1.1rem;
    }

    .info-section h4 {
        font-size: 0.95rem;
        margin-top: var(--spacing-sm);
        margin-bottom: var(--spacing-xs);
    }

    .info-section ul {
        font-size: 0.85rem;
        padding-left: 1.2rem;
        margin: 0;
    }

    .info-section li {
        margin-bottom: var(--spacing-xs);
    }

    footer {
        padding: var(--spacing-md) var(--spacing-sm);
    }

    footer h3 {
        font-size: 1rem;
        margin-bottom: var(--spacing-sm);
    }

    footer ol {
        font-size: 0.8rem;
        padding-left: 1.2rem;
    }

    footer ol li {
        margin-bottom: var(--spacing-xs);
        line-height: 1.4;
    }

    footer p {
        font-size: 0.8rem;
        margin: var(--spacing-xs) 0;
    }

    footer a {
        font-size: 0.8rem;
    }
}